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There was a significant reduction in LS-mean change from baseline in AUC Glucose0-2h at 12 weeks both in the high GLP-1 and low GLP-1 groups with a greater degree of reduction seen in the high GLP-1 group compared to the low GLP-1 group by -156.26 mmol/L.min (95% CI -272.81, -39.72 mmol/L.min)

These participants were randomly assigned to take either tirzepatide or semaglutide at their highest tolerated doses

Each peptide contributes a unique area of scientific interest

Ozempic (semaglutide) is an FDA-approved glucagon-like peptide-1 (GLP-1) receptor agonist used for type 2 diabetes