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The most commonly reported events were decreased appetite (19%), headache (12%), fatigue (11%), and COVID-19 infection (11%), most of which were mild

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Retatrutide is an investigational GLP-1, GIP, and glucagon triple receptor agonist available only through authorised clinical trials

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Time-to-onset analysis revealed a median latency of 32 days (IQR 7122) for GLP-1 RA-related NAEs, with 45.28% occurring within 30 days of treatment initiation