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The hypothalamus and enteric nervous system of the gastrointestinal tract also produce small amounts of dopamine

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Additionally, fatigue emerged as a frequently discussed symptom, despite being less prominent in clinical trial data

1 Introduction Substance use disorders (SUDs) represent a major global public health challenge, contributing significantly to morbidity, premature mortality, and socioeconomic burdens ( One promising strategy involves repurposing existing medications with well-established safety profiles ( Despite promising findings in animal studies, human studies remain limited