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10.1016/j.jnutbio.2007.06.010

Our present study identifies an important role for GLP-1R in diabetes treatment, highlights the potential of natural plant-derived substances in the treatment of diabetic cognitive impairment, and provides new ideas for the future development of drugs to treat diabetic cognitive dysfunction

TB-500 is a synthetic fragment of Thymosin Beta-4, a 43-amino acid protein involved in actin regulation and cytoskeletal organisation, with a molecular formula of CHNOS and molecular weight of approximately 4,963 g/mol

10.1038/s41398-019-0525-3 420 SutherlandV

The major part of the flux is carried by the low affinity transporter, which has sigmoidal kinetics with a V max in the range 9001400 M/hr, a K m of approximately 3000 M, and a Hill coefficient of approximately 3 [3436]