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Description

GLP-1 immunoreactive fibers and nerve terminals are distributed in the parvocellular parts of the PVN and innervate this structure, directly connecting GLP-1 with the CRH neurons [72]

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Cognitive scores, measured by the Mattis DRS-2, depicted a 5-point advantage at 12 months, a 6.3 advantage at 14 months, and a 5.3-point advantage at 24 months of exenatide compared to controls [86]

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Samples were centrifuged at 5000 g for 30 seconds, and bead pellets washed 3 in 500 L wash buffer (50 mM Tris-HCl, 150 mM NaCl, pH 7.4) before storage at 80 C until further analysis

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