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Abbreviations CVE: Cardiovascular event EHR: Electronic health record GLP-1RA: Glucagon-like peptide-1 receptor agonist MACE: Major adverse cardiovascular events NAFLD: Non-alcoholic fatty liver disease NASH: Non-alcoholic steatohepatitis PCI: Percutaneous coronary intervention PSM: Propensity score matching SGLT2: Sodiumglucose cotransporter 2 SMD: Standardised mean difference TG: Triacylglycerol References Younossi ZM, Koenig AB, Abdelatif D, Fazel Y, Henry L, Wymer M (2016) Global epidemiology of nonalcoholic fatty liver disease-meta-analytic assessment of prevalence, incidence, and outcomes

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Moreover, experimental evidence demonstrates that calcitriol enhances the expression of multiple tight junction proteinsincluding claudin-4/7, occludin, and ZO-1via activation of PI3K/Akt and atypical PKC (aPKC) signaling pathways, thereby significantly increasing transepithelial electrical resistance (TER) and reinforcing barrier homeostasis [109]

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