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If someone had gastric lesions compared to, lets say, distal GI (theyre color lesions), would you say oral would be better for gastric and then injectable would be better for the colon
Protocols, doses, and reactions reported below come from published clinical trials (each compound studied separately and one combination not involving retatrutide) and self-reported community sources
However, in recent years, there have been few studies that systematically analyze the potential mechanisms in this field
This PK-PD disconnect is compatible with a peptide whose mechanism triggers downstream signalling cascades (VEGFR2 activation, fibroblast migration, angiogenesis) that persist well beyond direct peptide presence
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