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Its primary mechanism in a research setting involves the upregulation of the Early Growth Response-1 (EGR-1) gene

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Melatonin biosynthesis is synchronized with the cycle of light and dark with serum melatonin concentrations following a circadian rhythm, playing a direct role in the bodys sleep cycle and thermoregulation [63]

Potential side effects can include bruising at the cannula site, a temporary drop in blood pressure (particularly with rapid magnesium delivery), nausea, or lightheadedness