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The analysis could be affected by residual confounding from unsupervised lifestyle modifications, and importantly, the reasons for treatment discontinuation were not recorded

Our results suggest that semaglutide reduces physical activity not through energetic impairment, but by attenuating behavioral motivation, likely via overlapping mechanisms that also mediate food seeking and reward valuation

Their cardiometabolic improvements reflected similar results

Lack of self-administration and behavioural sensitisation to morphine, but not cocaine, in mice lacking NK1 receptors

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