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Participants were randomized in a 1:1 ratio to receive Mazdutide 6 mg or Semaglutide 1 mg for 32 weeks, & in the extension period, participants originally on Mazdutide were assigned to continue Mazdutide treatment at different doses for another 24 weeks, based on whether they achieved the weight-loss target

To calculate the relative protein expression, we calculated the ratio of the target proteins grayscale value to that of the reference protein

GLP-1s can induce nausea or digestive disturbances, potentially muddying the recovery waters

Holding the pen pointing needle-end up, press the dose button on the other end until the dose counter goes to zero and a tiny drop appears at the tip of the needle

Thats the heart of the question many of us bring to the clinic: your goals, medical history, and tolerance for side effects matter