The purpose of surgery was the creation of a duodenocutaneous fistula (2 mm diameter duodenum (at ventral side, 2 mm from pylorus) and 3 mm diameter skin defect at the proximal third part of medial incision, where a precise caliper was used to verify the initial size of the defect), as described before (11)

Ideal Candidates Include: People with Metabolic Dysfunction: Type 2 diabetes or pre-diabetes Insulin resistance Metabolic syndrome Obesity or trouble losing weight High triglycerides or cholesterol Fatty liver disease (NAFLD) PCOS (polycystic ovary syndrome) Those Experiencing Low Energy and Fatigue: Chronic fatigue syndrome Mitochondrial dysfunction Low energy despite adequate sleep Poor exercise tolerance or endurance Difficulty recovering from physical activity Athletes and Active Individuals: Wanting to improve endurance capacity Seeking better recovery between training sessions Looking to optimize body composition Aiming to enhance metabolic efficiency Preparing for competitions or events Aging Adults Focused on Longevity: Age 40+ seeking to prevent metabolic decline Interested in health span extension Wanting to maintain muscle mass and function Concerned about age-related disease prevention Seeking cognitive protection as they age Anyone Struggling With: Weight loss resistance despite diet and exercise Visceral (belly) fat accumulation Poor metabolic flexibility Brain fog and cognitive issues Declining physical performance with age Combining MOTS-C With Other Therapies MOTS-C works synergistically with other metabolic optimization strategies, often producing enhanced results when properly stacked

These amino acids support the release of human growth hormone (hGH) from the brain
Santy LC, Casanova JE (2001) Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D
753 Registered nurses, licensed practical nurses, licensed psychologists, rehabilitation specialists and social workers also play vital roles in the coordination and delivery of care for people living with dementia