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Also noted in the original genome publication was the presence of the orphan genes syeAB (originally yba34 ), for which functions have remained entirely unknown

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Caspase-9 then cleaves and activates the effector caspase-3, leading to the cleavage of specific intracellular proteins and cell death [57, 58]

Mitochondrial Origin = Metabolic Power Unlike typical peptides, MOTSc is synthesized in response to cellular energy demandsparticularly when glucose is scarce or when the body is under stress