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Age-related changes can affect your B12 levels Older adults can be susceptible to B12 deficiency because sometimes aging is concurrent with decreased absorption of the vitamin, Yourman says

Oxidative stress damages cellular structures, accelerates aging, and contributes to follicle miniaturization

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Rheumatic disorders As adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in: Post-traumatic osteoarthritis Synovitis of osteoarthritis Rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require low-dose maintenance therapy) Acute and subacute bursitis Epicondylitis Acute nonspecific tenosynovitis Acute gouty arthritis Psoriatic arthritis Ankylosing spondylitis 3

B12 injection side effects Vitamin B12 shots are generally well tolerated