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DIO2 Thr92Ala reduces deiodinase-2 activity and serum-T3 levels in thyroid-deficient patients

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Published in the Journal of Clinical Endocrinology and Metabolism (N=65 adults) showed CJC-1295 with DAC produced dose-dependent increases in mean GH concentrations of 2 to 10-fold and sustained IGF-1 increases for up to 28 days after a single injection [2]