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And according to the 2020-2025 Dietary Guidelines for Americans by the U.S

Explor Drug Sci

News Large-scale analysis of more than 400,000 Reddit posts has identified patient-reported symptoms associated with glucagon-like peptide-1 receptor agonists that may not be fully captured in clinical trials, with reproductive and temperature-related effects emerging as signals for further investigation in real world evidence A research team at the University of Pennsylvania, Philadelphia, USA, has used artificial intelligence to analyse more than 400,000 Reddit posts and identified patient-reported symptoms associated with glucagon-like peptide-1 (GLP-1) receptor agonists that may not have been explored in randomised clinical trials (RCTs) or regulatory documentation

This increases the reabsorption burden of the renal tubules, resulting in impaired excretion of renal metabolic waste and contributing to the increase in BUN

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