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Mariani E, Ravaglia G, Forti P, Meneghetti A, Tarozzi A, Maioli F, et al

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"Our study highlights several biological pathways by which GLP1 drugs may influence Alzheimer's, including reducing inflammation, improving insulin signaling in the brain, and altering enzymes involved in the production of amyloidbeta." GLP-1 drugs get their name from the glucagon-like peptide-1 (GLP-1) hormone that they mimic

GSM-directed therapy in peri/postmenopausal patients (or others with hypo-oestrogen states): NICE and UK resources support vaginal oestrogen as a local therapy for genitourinary symptoms of menopause, with patient counselling that systemic absorption is minimal and serious adverse effects are very rare

This might be due to the side effects of niacin, or vitamin B3