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The studies began with the determination of the optimal dosing for Cagrilintide in both chow-fed and high-fat diet (HFD)-fed wild-type (WT) mice, followed by analyses of its receptor dependence using receptor activity-modifying protein (RAMP) knockout (KO) models, and mechanistic studies involving neuronal activation and gene expression profiling [2]

Recent Prog Horm Res, 50: p

doi: 10.1186/s12916-023-03146-5

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Gastroenterology 151 , 945960.e946 (2016)