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Between the two, semaglutide and tirzepatide consistently lead the clinical data, and the right choice usually depends on BMI, metabolic history, and how the body responds to the starting dose

The escalation protocol has six steps instead of five

Semaglutide and tirzepatide, among other GLP-1 medications, have demonstrated: Significant weight reduction (often over 10% of body weight) Improved glycemic control Cardiovascular benefits (including lower risk of major adverse cardiac events) In pivotal trials like the STEP (semaglutide) and SURMOUNT (tirzepatide) studies, frequent in-person weight monitoring typically every 2 to 4 weeks was an integral component of optimizing these outcomes

The genetic test does not predict exact medication response or guarantee which formulation will work best for you

Nadolsky shares he often gets backlash for his take on the question: is obesity a choice