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This structural alteration is believed to facilitate more sustained engagement with intracellular signaling cascades

In the presence of peroxides, the selenolate form of GPX4 is oxidized to selenic acid, which is regenerated to its active form by two molecules of reduced GSH, converting lipid hydroperoxides into non-toxic lipid alcohols and generating oxidized GSH (16,9294)

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Transfer hydrogenation catalysis in cells as a new approach to anticancer drug design