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: #CardiovascularInnovation #Hypertension #MarketAccess #PayerStrategy #MedicalAffairs Leonardo Faria Charlotte Soul To view or add a comment, sign in Thrilled to share our latest Research

Abstract Objective Type 2 diabetes mellitus (T2DM) increases the risk of sarcopenia, but evidence on the effects of glucagon-like peptide 1 receptor agonist (GLP-1 RA) in skeletal muscle is limited and inconsistent

However, increased glycolysis may lead to myocardial hypertrophy, necessitating the prioritization of FAO to alleviate cardiac hypertrophy

That is a different story from spacing doses under supervision. What structured de-escalation is and what it is not The authors described reduced-frequency maintenance as structured de-escalation that could reduce treatment burden without sacrificing key outcomes, at least in selected patients

Challenges Limited clinical evidence: The main bottleneck in the market is the low clinical evidence, which is often confused with broader health claims