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However, during ovarian aging, defects in PINK1/Parkin-mediated mitophagy further promote ferroptosis and apoptosis (Khan et al., 2023

And you do a bit on that

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Blocking the interaction between PIN-1 and MAT1 reversed the alcohol-induced cytotoxic phenotype

In order to elucidate the inhibition mechanism of HQ, we solved two crystal structures of TyrBm with HQ in the active site