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Annual OGTT from age 10 is the preferred screen for cystic fibrosisrelated diabetes

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Reduced appetite as we get older can make this worse

Disruptions within this axis such as leptin resistance in obesity or impaired GLP-1 signaling in diabetes are not merely consequences of these diseases but active contributors to their pathogenesis by distorting taste preferences and perpetuating pathological eating behaviors

While these do not predict exact medication response, they may help your provider contextualize your metabolic profile and decide whether liraglutide, semaglutide, tirzepatide, or another approach aligns with your genetics and health goals