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No current research has evaluated its effect on mortality or cardiovascular, diabetes-related, or other outcomes

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Key variables such as the degree of weight loss, medication adherence, timing and duration of GLP-1RA exposure relative to the BOTOX index event, and behavioral or lifestyle factors were unavailable and may have influenced the observed associations

21 Remarkably, even in HF-free patients with morbid obesity, cardiac abnormalities can be seen that are consistent with left ventricular (LV) remodelling and dysfunction, including greater LV mass, LV diastolic dysfunction and elevated LV filling pressure