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10.1038/s41419-018-1063-2 92 WayJ

Frameshift variants often cause premature truncation of the protein, leading to loss of function and widespread multisystem involvement, as seen with visceral anomalies and cognitive impairment

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Peptide Profile Compound Semaglutide CAS Number 910463-68-2 Molecular Formula CHNO (structure-dependent) Molecular Weight ~4113.6 g/mol Sequence Modified GLP-1 analogue peptide with structural modifications Purity 99% (HPLC) Form Lyophilised peptide (solid cake) Appearance White to off-white lyophilised solid Usage & Storage Intended Use Semaglutide is a synthetic peptide supplied for laboratory research applications, including biochemical and analytical studies