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Recent advancements have introduced the nsMRA, finerenone, which may offer a lower risk of hyperkalemia compared to traditional sMRAs, potentially allowing broader use in patients at risk of hyperkalemia

It can cause dangerous blockages, be life-threatening, and may require surgery or urgent medical attention to correct

For instance, the IMPROVE HF study, which included 15,381 HFrEF patients, identified several factorsfemale sex, no prior myocardial infarction, nonischemic heart failure etiology, and absence of digoxin useas being associated with a greater than 10% improvement in EF 23

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While this reduced appetite can help with calorie control, it also comes with a risk: inadequate protein intake , which can lead to loss of muscle mass if not carefully managed