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FIGURE 1 Given the role of GLP-1 in glycaemic control, the anti-apoptotic, growth-stimulating and insulin secretion-promoting effects on pancreatic -cells, the ability to re-sensitize the cellular insulin-signaling, minor side effects, good tolerance by normoglycemic patients and the fact that GLP-1 does not desensitize, synthetic GLP-1R agonists have been on the market for decades to treat type 2 diabetes mellitus (T2DM) or, more recently, to improve weight loss (Drucker, 2018)

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For many people, this means eating less without feeling as though they're constantly fighting hunger

Heart failure (HF) is a major cardiovascular complication of T2DM, with affected individuals having an approximately 1.6 to 2-fold higher risk of incident HF than those without diabetes [4]

Only 3 weeks in so no weight lose yet but I do feel the feeling of fullness and less desire of food