The important considerations include: You are an adult with obesity or dealing with weight-related problems You are an individual with a BMI of more than 30 kg/m You are an adult with overweight conditions such as having a BMI of more than 27 kg/m and having weight-related problems like Type 2 diabetes, high blood pressure, or high cholesterol
Chronic neuroinflammation, characterized by microglial activation and cytokine release, disrupts synaptic plasticity and leads to neuronal death, ultimately causing memory and learning deficits (Wu et al., 2025)
Proper dose titration ensures both efficacy and tolerability data are captured
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This means your peaks are sharper, your troughs are deeper (proportionally), and the wearing-off effect may be more pronounced
