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By contrast, for the intravenous (IV) preparation, the UK licence recommends a dose of 4 g/day every 46 h for adults weighing above 50 kg with a dose reduction to 3 g/day in those who have risk of hepatotoxicity

The resin was washed by ten volumes of wash buffer (50 mM Tris-HCl, pH 8.0, 400 mM NaCl, 1 mM CaCl 2 , 5% glycerol, 0.05% DDM) and mIGF1R protein was eluted by HRV-3C protease cleavage