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For context, the dual agonist tirzepatide is studied in SURMOUNT ( NEJM , 2022) and SURMOUNT-OSA ( NEJM , 2024)

Semaglutide Contains one mechanism of action: A GLP-1 agonist Decreases appetite, increases production of insulin, and increases satiety Used for patients seeking weight loss, patients suffering from Polycystic Ovarian Syndrome (PCOS), and those with insulin resistance

Focus on fiber-rich foods, lean proteins, healthy fats and fermented foods

Personalization and Genetic Testing Advantages The PlexusDx Precision Peptide Genetic Test ($99 add-on after your first month) analyzes GLP1R (rs6923761), GIPR (rs1800437), and FTO (rs9939609) variants that relate to GLP-1 and related signaling pathways

Injectable GHK-Cu Users Injectable GHK-Cu is used for more systemic effects: Systemic anti-aging and gene expression modulation Enhanced wound healing for deep-tissue injuries Systemic anti-inflammatory effects Comprehensive regenerative protocols (often combined with other peptides) Injectable users tend to be patients in more intensive anti-aging or regenerative programs supervised by specialized practitioners