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Tirzepatide is a dual agonist, targeting the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, while retatrutide is a triple agonist, targeting GIP, GLP-1, and GCG simultaneously

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This depends on dose and vial size: 2mg vial at 200mcg/dose = 10 doses 2mg vial at 300mcg/dose = 6.6 doses (approximately 6) 5mg vial at 200mcg/dose = 25 doses 5mg vial at 300mcg/dose = 16.6 doses (approximately 16) At a standard protocol of 200-300mcg once or twice daily, a 5mg vial lasts 8-25 days depending on frequency and dose

Future research should focus on elucidating the complex mechanisms underlying their psychological effects and integrating mental health considerations into therapeutic strategies