For those who require maximal weight loss, such as people managing severe obesity alongside cardiovascular risk or obstructive sleep apnoea, injectable therapy may remain the medically preferred route
For laboratory in-vitro use only
86,87 Differing from the effects observed in T2DM, the therapeutic efficacy of dulaglutide for MASLD is not particularly compelling based on current statistics
This is why Tirzepatide (Mounjaro/Zepbound), which combines GLP-1 and GIP, produces better results than Semaglutide alone while causing less nausea (25% versus 44%)
In addition, data on suicide risk in patients on incretin therapies may be confounded by underlying conditions, including obesity and diabetes, which have been linked to increased suicide risk