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Our study provides evidence that PDS5B acts in synergy with BRCA2-DSS1 in the assembly of RAD51-ssDNA presynaptic filaments, but whether PDS5B also cooperates with BRCA1-BARD1, PALB2, and complexes of the RAD51 paralogs in presynaptic filament assembly and in RAD51-mediated DNA strand exchange remains to be determined

In the absence of the mouse DNA/RNA-binding protein MSY2, messenger RNA instability leads to spermatogenic arrest

Minucci S, Pelicci PG

For the preclinical studies outcomes were subdivided in the following domains: depressive-like behavior, anxiety-like behavior, cognition and social behavior

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