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Nausea affects more than 1 in 10 patients and results from delayed gastric emptying and direct stimulation of brainstem nausea pathways

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11 Other glucose-lowering treatments can be continued if needed for glycaemic control or cardiovascular or renal protection, with the dose of insulin or a sulfonylurea reduced to prevent hypoglycaemia, if required (see: Prescribing empagliflozin for guidance on dose reduction)

doi:10.1177/0269881110379283 Bergamaschi MM, Queiroz RH, Chagas MH, et al