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In the Sibutramine Cardiovascular Outcomes (SCOUT) trial, the drug was shown to be associated with increased risk of major adverse cardiovascular events (a composite of non-fatal heart attack, non-fatal stroke, resuscitation after cardiac arrest, and cardiovascular death) in obese patients, as compared to placebo [29]

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

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As a cytoprotective agent, mediating Roberts cytoprotection, it maintains endothelium integrity and has a particular angiomodulatory effect (Sikiric et al., 1993

We use many different natural medicines in our shot formulas