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These findings lend support to the hypothesis that the increase in SHBG levels induced by liraglutide might contribute per se to reduce the risk of developing the metabolic syndrome in PCOS, also considering the effect of SHBG in directly suppressing inflammation and lipid accumulation in macrophages and adipocytes [65]

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Hormonal modulation is involved in the anabolic and catabolic processes as well

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These functions occur via binding and activation of their cognate secretin-like (class B) G protein-coupled receptors (GPCRs)