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On top of that, interactions of biomaterials with erythrocytes, which are the most abundant cells in circulation, are mainly evaluated by in vitro hemolysis testing [465, 466]

While dihexa at 1 nM and 10 pM alone does not activate c-Met, it markedly augments the capacity of HGF at 1.25 and 2.5 ng/mL to activate c-Met

Later, it was discovered that mitochondrial DNA encodes its own small biologically active peptides that are released from the mitochondria and act as hormone-like signaling molecules throughout the body

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10.1038/s41598-018-20164-z 76