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In summary, SIRT1 emerges as a plausible integrative node linking oxidative stress, mitochondrial dysfunction, metabolism and inflammation to nociceptive sensitisation in FM

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The murmur sound is caused by the turbulent flow of blood jetting backwards through the damaged leaflets of the mitral valve from the left ventricle, into the left atrium

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Exploiting the high metabolic capacity of tumor cells, certain chemotherapeutic drugs like sorafenib and sulfasalazine induce ferroptosis in various cancer types

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