Folate, vitamin B6, and vitamin B12 deficiencies are due to poor dietary intakes, illness, genetic defects that result in impaired absorption or transport, or a combination of these factors.9 Although clinical deficiencies of these vitamins are uncommon in the United States and are usually limited to individuals with genetic mutations, low or marginal deficiencies have been reported, particularly among nonwhite and elderly populations, and women of childbearing age
their hyperthyroid state may be induced by supplementation of thyroid hormones such as thyroxine (T4) or triiodothyronine (T3), or by the administration of thyroid-stimulating immunoglobulins to induce Graves disease, one of the autoimmune forms of hyperthyroidism (Zhang et al
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Front Endocrinol (Lausanne) (2021) 12:706978
Chronic hyperglycemia induces a proinflammatory state characterized by elevated levels of cytokines such as tumor necrosis factor-alpha (TNF-), interleukin(IL)-1 beta, and IL-6