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Consistent with the phosphorylation of Met and the subsequent signalling proteins, the dimeric macrocycles are able to clearly mimic the functional role of hHGF and induce cellular responses in not only model cell lines but also various normal human cells (Figs 4, 5, 6 and Supplementary Figs 13 and 14)

Unlike many peptides that degrade quickly in acidic environments, BPC-157 is notable for its stability in gastric conditions, which led researchers to study its potential effects on the digestive system

Treatment of HUVECs with BPC-157 (1 g/mL, 5 g/mL, and 10 g/mL) enhanced cell motility in a concentration-dependent manner compared with untreated cells

This rapid chemical reaction at the injection site can activate pain receptors, resulting in a classic burning sensation