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In addition, aggregated Amyloid- activates the p38 mitogen activated protein kinase (MAPK) in cell leading to hyperphosphorylation of protein Tau and formation of neurofibrillary tangles (NFTs) inside neurons, making the microtubules unstable and causing the loss of neuron functionality [80]

N., Angelopoulou, E., Piperi, C., Shaikh, M

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DPP-4i could reduce BP by improve IR, particularly in patients with T2DM

While everyone's weight journey is different and the amount of weight loss varies for everyone, most patients taking weight loss medications who follow a healthy diet and regular exercise lose 1-2 pounds per week