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There is an urgent need to incorporate multidisciplinary care in the identification of high-risk patients who may benefit from these agents [24]

L-Carnitine is an amino acid found in high concentrations in heart and liver tissues where, inside the cells (mitochondria), L-Carnitine helps transform fats into energy (i.e., ATP)

In addition, it has also shown that butyrate stimulated PGC-1 activity by activating AMP-activated protein kinase (AMPK) and inhibiting histone deacetylases (116)