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Another study found that people with opioid or alcohol use disorder who took GLP-1s had a 40% lower rate of opioid overdose and a 50% lower rate of alcohol intoxication than people who weren't on the medications

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Animals fed with excess iron demonstrate increased lipid peroxidation, BBB breakdown, altered mitochondrial dynamics, -amyloid deposition, tau hyperphosphorylation, and loss of dendritic spine densityreminiscent of AD pathology (Sripetchwandee et al., 2014, 2016)

Obesity and diabetes as accelerators of functional decline: can lifestyle interventions maintain functional status in high risk older adults

Tome-Carneiro J, Visioli F