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The hazard ratios (HRs) comparing tirzepatide to controls were 0.80 (95% CI, 0.571.11) for MACE-4, 0.90 (95% CI, 0.501.61) for cardiovascular death, and 0.80 (95% CI, 0.511.25) for all-cause death

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For example, in clinical trials a GLP-1 analog (ROSE-010) significantly retarded gastric emptying in IBS patients, confirming that GLP-1 activity slows upper GI tract movement

In accepting the hypothesis of G6PD deficiency as a predisposing factor to coronary atherosclerosis, its role may be outweighed by the other, nonmodifiable (e.g., age) and modifiable cardiovascular risk factors, in relation to the prevalence and clustering of these factors in the different study populations, which justifies the conflicting study results, at least in part