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We can make hypotheses about penetration and efficacy based on chemical structure, but we need real-world, high-quality data before we can know if something like this is effective and safe, says Dr

Others who might be prescribed B12 shots are those at the highest risk for a B12 deficiency, including: Vegans, since vitamin B12 is found only in animal products People ages 60 and up since their bodies don't absorb B12 as efficiently People with Crohn's disease or pancreatic disease, since they prevent nutrient absorption People who had weight-loss surgery, which decreases B12 absorption People with an eating disorder People with HIV People with diabetes Since a mild B12 deficiency might not cause symptoms, it can go undetected for years since levels are not checked during routine blood work

These can support researchers in finding trusted compounds they need for experimental work

[Google Scholar] 21.Wharton S, Batterham RL, Bhatta M, Buscemi S, Christensen LN, Frias JP, et al

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