Weight loss is sustainable while continuing the medication
Adequate protein intake, hydration, collagen supplementation , and resistance training help minimize loose skin
It can show up as a snacky feeling, so we go look in the cupboard or fridge for something to eat even though our brain is asking for water, Salamon says
Key medications your provider will flag include insulin and sulfonylureas (because combining them with GLP-1 medications increases the risk of hypoglycemia and doses may need adjustment), warfarin and other anticoagulants (because changes in absorption could affect clotting times), levothyroxine (because absorption may be delayed, though clinical significance is debated), oral contraceptives (because absorption timing may shift, though most providers consider this a low risk with modern formulations), and certain antibiotics and antiretroviral medications
This continuous approach prevents the biological rebound cycle entirely rather than fighting it after discontinuation