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The data showed that with weekly administration, it normalized glucose tolerance and led to weight loss by the reduction of food intake and increased energy expenditure in obese mice [41]

Further evaluation, including electrocardiography, echocardiography, and carotid echo-Doppler examination, can be performed if clinically indicated (23)

Cheng SB, Dong J, Pang Y, et al

Smoking, obesity, and alcoholism can deplete this nutrient, which would counteract the benefits of the therapy

However, this method has problems associated with highly complicated reaction steps and the use of a heavy metal such as lead tetraacetate (Pb(CH COO) )