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Also, to assess the AES symptoms, items from a previously established questionnaire available in the cohort were utilized, following theoretical models and earlier research findings

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[DOI] [PMC free article] [PubMed] [Google Scholar] 183.Ebersbach C., Beier A.-M.K., Thomas C., Erb H.H.H

Studies suggest that a significant proportion of long-term metformin users may develop biochemical B12 deficiency, though estimates vary widely depending on the population studied, the duration of use, and the B12 threshold applied