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These pathogenic bacteria can colonize the gut by exploiting epithelial damage and activate TH1/TH17 immune responses through virulence factors, such as the type III secretion system ( The data mentioned above indicate that the pathogenic potential of specific microorganisms in IBD is subject to multifactorial regulation, encompassing genetic background, environmental factors, and the composition of the gut microbiota

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Free Radic Res 44(7):72133