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Advanced approaches utilize biotin hydrazide or other tagged hydrazides for carbonyl derivatization, enabling avidin-based affinity chromatography enrichment before LC-MS/MS identification of modified proteins and specific carbonylation sites (Madian and Regnier, 2010)

These primary cell models are of high translational value

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One critical area of focus is cellular oxidative stress and the depletion of a vital molecule known as glutathione

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