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Here, we examined the effectiveness of supplementation with the endogenous antioxidant glutathione (GSH) during anti-diabetic treatment

As PGA is linked to perturbations in the -glutamyl cycle and glutathione metabolism, these findings are consistent with reduced antioxidant reserve or increased antioxidant demand in affected individuals

This binding is quite tight and facilitates their excretion via the urine

As an important target for inducing ferroptosis, System X c can provide a new direction for the treatment of drug-resistant solid tumors

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